How Do You Spell TRANSFORMED CELL LINE?

Pronunciation: [tɹansfˈɔːmd sˈɛl lˈa͡ɪn] (IPA)

The term "Transformed Cell Line" refers to a group of cells that have undergone genetic alteration to develop different characteristics, typically for laboratory research purposes. In phonetic transcription, it would be spelled as /trænsˈfɔrmd sɛl laɪn/. The first syllable "trans" is pronounced as "træns" with a short "a" sound. The second syllable "formed" is pronounced as "ˈfɔrmd" with stress on the first syllable. Lastly, "cell line" is pronounced as "sɛl laɪn" with the stress on the second syllable of "line."

TRANSFORMED CELL LINE Meaning and Definition

1. A transformed cell line refers to a population of cells that have undergone genetic modification to possess properties that differ from their original state. It is typically achieved through a process known as cellular transformation, where normal cells are subjected to various external factors, such as exposure to chemicals or infection with viruses, that cause permanent alterations in their genetic material.

   The genetic modifications in transformed cell lines often result in increased cell division rates, loss of contact inhibition (the normal process that prevents cells from dividing when they come into contact with each other), and the ability to form tumors. These characteristics make transformed cell lines valuable tools in various fields of research, including cancer biology, immunology, and drug development.

   Transformed cell lines can be derived from different cell types, including human and animal cells. They are commonly used in laboratories to study the biological processes underlying disease development, test the efficacy and toxicity of potential therapeutic compounds, and investigate the mechanisms of action of various biological agents.

   The establishment of transformed cell lines involves isolating and propagating cells that have acquired transformative properties. Once the cell line is established, it can be maintained in culture for prolonged periods, allowing researchers to conduct numerous experiments over time. Transformed cell lines are often characterized by specific markers or genetic alterations that distinguish them from their normal counterparts.

Common Misspellings for TRANSFORMED CELL LINE

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