How Do You Spell TOPHI?

Pronunciation: [tˈɒfa͡ɪ] (IPA)

Tophi is spelled with four letters and two syllables. The first syllable is pronounced as 'toh' with the long o sound, and the second syllable is 'fee' with the short i vowel sound. The IPA transcription of Tophi is /ˈtoʊ.fi/. The word is derived from the Greek term "tophos" which means stone. It refers to the small, hard, and chalky deposits that form in the joints of people with gout. Tophi can cause pain, inflammation, and stiffness, and they often require medical attention.

TOPHI Meaning and Definition

1. Tophi are defined as small, hard, and nodular accumulations of urate crystals that form primarily in the joints and soft tissues of individuals affected by chronic gout. Gout is a type of inflammatory arthritis caused by the deposition of uric acid crystals in the joints, resulting in severe pain and swelling.

   The formation of tophi occurs when urate crystals, formed due to elevated levels of uric acid in the blood, gather and accumulate in the connective tissues surrounding the joints. These deposits typically develop over a prolonged period of time, as chronic gout progresses and remains untreated or poorly managed.

   Tophi initially appear as small, whitish, and chalky lumps under the skin, generally visible near the affected joints. As they grow larger, tophi can cause disfigurement and deformity of the joints, resulting in limited mobility and functional impairment. They may also develop internally, affecting organs such as the kidneys.

   The presence of tophi is considered a clinical manifestation of advanced gout, indicating a chronic and ongoing condition. Treatment for tophi includes addressing the underlying gout through medications aimed at reducing uric acid levels and preventing further crystal formation. In some cases, surgery may be necessary to remove tophi that are causing significant discomfort and joint damage. As tophi may be a sign of uncontrolled gout, prompt medical attention and management are essential to prevent further complications and alleviate symptoms associated with this condition.

2. Plural of tophus.

   A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

Common Misspellings for TOPHI

• gophi
• Tothi
• Torhi

Etymology of TOPHI

The word "tophi" is derived from the Greek word "tophos", which means "lime deposit". It entered the English language in the mid-18th century, specifically to refer to the chalky deposits of uric acid crystals found in the joints or other tissues of individuals suffering from gout. Gout is a type of arthritis caused by an excess buildup of uric acid in the body, leading to the formation of these tophi.