TIENILIC ACID Meaning and
Definition
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Tienilic acid is a noun that refers to a white crystalline compound with the chemical formula C9H6O4S. It is a pharmaceutical substance formerly used as a diuretic and uricosuric agent to treat conditions such as edema and excessive uric acid levels in the blood.
The compound belongs to the class of thienothiazine derivatives and is characterized by its sulfinyl group (-S(O)-) attached to a thiazine ring. Tienilic acid acts by inhibiting the reabsorption of sodium and chloride ions in the kidneys, promoting the excretion of water and electrolytes. It also exhibits weak uricosuric properties by decreasing uric acid reabsorption, thereby assisting in the removal of excess uric acid from the bloodstream.
Due to its adverse effects on liver function and the potential to induce hepatic injury, the use of tienilic acid has been largely discontinued. Numerous cases of liver toxicity were reported, leading to its withdrawal from the market in many countries. The compound’s production has also been halted. Tienilic acid's hepatotoxicity was attributed to its metabolite, which led to the formation of reactive intermediates that caused liver damage.
In summary, tienilic acid is a sulfinyl-containing pharmaceutical compound used for its diuretic and uricosuric properties in the past. However, it has been discontinued and withdrawn from use due to associated liver toxicity and possible severe liver damage.
Common Misspellings for TIENILIC ACID
- rienilic acid
- fienilic acid
- gienilic acid
- yienilic acid
- 6ienilic acid
- 5ienilic acid
- tuenilic acid
- tjenilic acid
- tkenilic acid
- toenilic acid
- t9enilic acid
- t8enilic acid
- tiwnilic acid
- tisnilic acid
- tidnilic acid
- tirnilic acid
- ti4nilic acid
- ti3nilic acid
- tiebilic acid
- tiemilic acid
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