THIOSTREPTON Meaning and
Definition
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Thiostrepton is a noun that refers to a broad-spectrum antibiotic compound derived from certain strains of bacteria, particularly Streptomyces laurentii. It belongs to the thiopeptide class of antibiotics and is known for its potent antimicrobial activity against a variety of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE).
With a complex chemical structure, thiostrepton consists of macrocyclic lactone rings and sulfur-containing amino acid residues. This unique arrangement enables it to inhibit bacterial protein synthesis by binding to the large subunit of the ribosome, preventing the elongation phase and ultimately leading to bacterial cell death.
Thiostrepton exhibits a high degree of stability and resistance to degradation, which contributes to its prolonged duration of action and effectiveness against resistant strains of bacteria. Its mechanism of action is distinct from other antibiotics, making it a valuable therapeutic option for combating multidrug-resistant infections. Additionally, thiostrepton has been found to possess anti-inflammatory activity, making it beneficial in certain dermatological conditions.
Due to its potent antimicrobial properties, thiostrepton has shown promising results in both in vitro and in vivo studies. However, its usage is predominantly limited to laboratory research and as a topical treatment for certain infections in veterinary medicine. Further research and clinical trials are ongoing to evaluate its potential for human applications, with the aim of expanding its use as an effective and safe antibiotic agent.
Common Misspellings for THIOSTREPTON
- rhiostrepton
- fhiostrepton
- ghiostrepton
- yhiostrepton
- 6hiostrepton
- 5hiostrepton
- tgiostrepton
- tbiostrepton
- tniostrepton
- tjiostrepton
- tuiostrepton
- tyiostrepton
- thuostrepton
- thjostrepton
- thkostrepton
- thoostrepton
- th9ostrepton
- th8ostrepton
- thiistrepton
- thikstrepton
Etymology of THIOSTREPTON
The word "Thiostrepton" is derived from a combination of two parts: "thio" and "strepton".
1. "Thio": This prefix indicates the presence of a sulfur atom in a compound. It comes from the Greek word "theion", meaning "sulfur".
2. "Strepton": This part of the word refers to a streptomyces bacterium genus. Streptomyces are a group of bacteria known for producing various bioactive compounds, including antibiotics.
Therefore, "Thiostrepton" is a combination of "thio", indicating the presence of sulfur, and "strepton", referring to the streptomyces bacteria that produce this compound. Thiostrepton is an antibiotic produced by Streptomyces azureus, originally isolated from soil samples.
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