How Do You Spell THIOFLAVINE?

Pronunciation: [θˌa͡ɪə͡ʊflˈava͡ɪn] (IPA)

The word "thioflavine" is spelled as follows: /θaɪəˈflæviːn/. This word is a compound of two roots -- "thio" means "sulfur" and "flavine" refers to a yellow dye. Therefore, thioflavine is a yellow dye molecule containing sulfur atoms. The IPA phonetic transcription helps explain the pronunciation of each individual sound in the word, making it clear that it is a seven-syllable, twelve-letter word that is pronounced with a distinguishable emphasis on certain syllables.

THIOFLAVINE Meaning and Definition

1. Thioflavine is a term used to define a class of fluorescent dyes that have sulfur (thio-) containing aromatic heterocycles. These dyes are specifically designed to have high affinity and selectivity for certain molecular targets, particularly biomolecules like proteins and nucleic acids. Thioflavines have several applications, primarily in biology and medicine.

   In the context of protein research, thioflavines are commonly employed as staining agents to visualize and study the aggregation of amyloid proteins, which are associated with neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. The interaction of thioflavine with amyloid aggregates leads to a significant increase in fluorescence, allowing for their detection and quantification using spectroscopic techniques.

   Thioflavines also find use in nucleic acid research, where they can be employed as intercalating agents to bind and label DNA and RNA molecules. The fluorescence emitted by thioflavine upon binding to nucleic acids enables their visualization and analysis in molecular biology experiments.

   Furthermore, the unique spectroscopic properties of thioflavines, such as their emission intensity and fluorescence lifetime, make them useful in fluorescence microscopy and imaging techniques. Thioflavines with different structural variations and substitution patterns offer a range of fluorescent dyes with diverse properties, allowing for the specific targeting and visualization of various cellular components.

   Overall, thioflavine refers to a class of fluorescent dyes that are valuable tools in molecular and cellular biology, enabling the detection and analysis of specific biomolecules for various biomedical applications.

Common Misspellings for THIOFLAVINE

• rhioflavine
• fhioflavine
• ghioflavine
• yhioflavine
• 6hioflavine
• 5hioflavine
• tgioflavine
• tbioflavine
• tnioflavine
• tjioflavine
• tuioflavine
• tyioflavine
• thuoflavine
• thjoflavine
• thkoflavine
• thooflavine
• th9oflavine
• th8oflavine
• thiiflavine
• thikflavine

Etymology of THIOFLAVINE

The word "thioflavine" has its etymology rooted in the combination of two parts: "thio-" and "flavine".

1. "Thio-" is a prefix derived from the Greek word "théion", meaning "sulfur". In chemistry, the prefix "thio-" is used to indicate the replacement of an oxygen atom with a sulfur atom in a compound.

2. "Flavine" is derived from the Latin word "flavus", meaning "yellow". It is associated with the color yellow because many compounds with the suffix "-flavine" have a yellow appearance or possess yellow dyes.

Hence, when combined, "thioflavine" refers to a compound that contains a sulfur atom and is associated with the yellow color.

Plural form of THIOFLAVINE is THIOFLAVINES