THIOACETAZONE Meaning and
Definition
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Thioacetazone is a noun referring to a chemical compound used as an antimicrobial agent, primarily for the treatment of tuberculosis. It is categorized as a sulfonamide derivative with the chemical formula C6H7N3S and a molecular weight of 161.2 grams per mole.
Thioacetazone functions by inhibiting the synthesis of mycolic acids, a critical component of the bacterial cell wall in Mycobacterium tuberculosis, the causative agent of tuberculosis. By disrupting cell wall assembly, thioacetazone impedes the growth and replication of the bacteria, leading to the elimination of the infection.
This compound is typically administered orally, often in combination with other antitubercular drugs, such as isoniazid and ethambutol, in order to prevent the emergence of drug resistance. Clinical studies have highlighted thioacetazone's effectiveness in treating tuberculosis, particularly in countries with limited resources where alternative drugs may be less affordable or available.
However, the usage of thioacetazone has diminished in recent years due to various reasons, including the potential for severe side effects, such as skin reactions, hepatotoxicity, and hypersensitivity reactions. Additionally, increased instances of drug-resistant tuberculosis necessitate the development of more potent and safer alternatives.
Overall, thioacetazone remains a relevant compound in combatting tuberculosis, although its use has become less prevalent in modern clinical practice. Ongoing research aims to enhance the understanding of thioacetazone's mechanism of action and optimize its effectiveness while minimizing side effects.
Common Misspellings for THIOACETAZONE
- rhioacetazone
- fhioacetazone
- ghioacetazone
- yhioacetazone
- 6hioacetazone
- 5hioacetazone
- tgioacetazone
- tbioacetazone
- tnioacetazone
- tjioacetazone
- tuioacetazone
- tyioacetazone
- thuoacetazone
- thjoacetazone
- thkoacetazone
- thooacetazone
- th9oacetazone
- th8oacetazone
- thilacetazone
- thipacetazone
Etymology of THIOACETAZONE
The word "thioacetazone" has a combination of root words that provide insight into its etymology.
1. "Thio-" is a prefix derived from the Greek word "theion", meaning "sulfur". It is commonly used to indicate the presence of sulfur in a compound.
2. "Acetazone" is derived from "acet-", which comes from "acetic acid", a chemical compound found in vinegar. "Azone" is a suffix often used in pharmaceutical compounds to indicate a chemically active group.
Combining these elements, "thioacetazone" can be understood as a compound containing a sulfur atom and a chemically active group derived from acetic acid.
