TFVIIA Meaning and
Definition
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TFVIIA is an acronym that stands for "Tissue Factor Pathway Inhibitor, Active Form." It refers to a critical protein that plays a crucial role in the regulation of blood clotting and coagulation processes in the human body.
TFVIIA is produced and released by the endothelial cells lining the interior walls of blood vessels. When an injury occurs and the blood vessels are damaged, TFVIIA prevents excessive clotting and ensures that the blood clotting cascade is regulated appropriately.
This protein acts as an inhibitor by binding to the activated form of tissue factor, known as tissue factor-FVIIa complex. By forming this complex, TFVIIA directly inhibits the effects of FVIIa, a key factor that initiates the blood clotting cascade. By doing so, TFVIIA limits the excessive formation of blood clots and prevents the risk of thrombosis or blockage of blood vessels.
In addition to its role in regulating clotting, TFVIIA also exhibits anti-inflammatory properties. It helps to modulate the immune response to inflammation, thus contributing to the maintenance of a balanced immune system.
Understanding the function and regulation of TFVIIA is essential for unraveling the complex mechanisms of blood clotting and hemostasis. It has garnered significant interest in medical research, as abnormalities in TFVIIA activity have been linked to various pathological conditions, such as thrombotic disorders and excessive bleeding tendencies.
Common Misspellings for TFVIIA
- rfviia
- gfviia
- yfviia
- 6fviia
- 5fviia
- tdviia
- tcviia
- tvviia
- tgviia
- ttviia
- trviia
- tfciia
- tfbiia
- tfgiia
- tffiia
- tfvuia
- tfvjia
- tfvkia
- tfvoia
- tfv9ia
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