How Do You Spell TELOME?

Pronunciation: [tˈɛlə͡ʊm] (IPA)

The word "telome" is spelled with the phonetic transcription /ˈtɛləʊm/. The first syllable is pronounced as "tel" and both the "e" and "l" are pronounced separately. The second syllable is pronounced as "ome" with a long "o" sound and an "m" at the end. This word refers to the end sections of a chromosome that are repeated multiple times. In genetics, telomeres play an essential role in protecting chromosome stability and preventing damage during cellular division.

TELOME Meaning and Definition

1. Telome refers to the terminal portion of a chromosome that consists of repetitive sequences, often composed of telomeric DNA and associated proteins. Telomeres are found at the ends of linear chromosomes in eukaryotic cells and serve several critical functions. Their primary role is to protect the chromosome from degradation and fusion with adjacent chromosomes.

   Telomeres are composed of DNA sequences that are rich in guanine and cytosine nucleotides. In humans, the telomeric DNA sequence is typically TTAGGG, which repeats up to thousands of times in a tandem array. This repetitive sequence is believed to provide stability and protect the chromosome by forming specialized structures and serving as a buffer against the loss of genetic material during cell replication.

   Moreover, telomeres play a vital role in cellular aging and senescence. With each cell division, a small portion of the telomeric DNA is lost due to the inability of DNA polymerases to fully replicate the chromosome ends. This progressive telomere shortening acts as a molecular clock, eventually triggering cellular senescence or programmed cell death. Telomeres are also associated with various diseases, including cancer and certain genetic disorders, as aberrant telomerase activity can lead to unlimited cell proliferation and genomic instability.

   In summary, telome is the terminal portion of a chromosome, consisting of repetitive DNA sequences known as telomeres, which serve to protect the chromosome from degradation, fusion, and genomic instability. They play a crucial role in cellular aging, senescence, and disease.

Common Misspellings for TELOME

• telomee
• relome
• felome
• gelome
• yelome
• 6elome
• 5elome
• twlome
• tslome
• tdlome
• trlome
• t4lome
• t3lome
• tekome
• tepome
• teoome
• telime
• telkme
• tellme
• telpme

Etymology of TELOME

The word telome is derived from the Greek word télos, meaning end or goal, combined with the suffix -ome, used to indicate a part or a whole.

Plural form of TELOME is TELOMES