How Do You Spell TACROLIMUS?

Pronunciation: [tˈakɹəlˌɪməs] (IPA)

Tacrolimus is a medication used to suppress the immune system and prevent organ rejection after transplantation. The word is spelled with the initial "t" sound followed by "a," which sounds like "ah" in the International Phonetic Alphabet (IPA). The "c" is pronounced like "k," and the following "r" has a rolling "r" sound. The "o" and "l" are pronounced like "oh" and "ull," respectively. The second "i" sounds like "ih," and the "m" and "u" are pronounced normally. Finally, the "s" at the end is pronounced like "z."

TACROLIMUS Meaning and Definition

1. Tacrolimus, also known by its brand name Prograf, is a potent immunosuppressive medication primarily used in the prevention of organ rejection following transplantation. It belongs to a class of drugs called calcineurin inhibitors, which work by suppressing the immune system to prevent it from attacking transplanted organs or tissues.

   Tacrolimus is commonly prescribed for individuals who have undergone liver, kidney, heart, or lung transplantation, as well as for recipients of bone marrow transplants. By inhibiting the activity of calcineurin, a protein that plays a role in immune response, Tacrolimus effectively reduces the production of certain types of immune cells, including T-lymphocytes.

   The medication is typically administered orally or intravenously and is available in various forms, such as capsules, tablets, and injections. Its absorption may be influenced by food, so it is generally recommended to take it consistently either with or without meals.

   While Tacrolimus is primarily used in transplant patients, it may also be prescribed for the treatment of certain autoimmune disorders such as atopic dermatitis, psoriasis, and severe refractory ulcerative colitis. Its efficacy in these conditions is due to its ability to modulate the immune system and alleviate inflammation.

   Tacrolimus may have various side effects, including increased susceptibility to infection, high blood pressure, kidney dysfunction, gastrointestinal disturbances, and skin reactions. Regular monitoring of blood levels is often necessary to ensure the medication is within the therapeutic range and to minimize the risk of toxicity.

   It is important to note that the provided definition is for informational purposes only and should not be considered as medical advice.

Common Misspellings for TACROLIMUS

• racrolimus
• facrolimus
• gacrolimus
• yacrolimus
• 6acrolimus
• 5acrolimus
• tzcrolimus
• tscrolimus
• twcrolimus
• tqcrolimus
• taxrolimus
• tavrolimus
• tafrolimus
• tadrolimus
• taceolimus
• tacdolimus
• tacfolimus
• tactolimus
• tac5olimus
• tac4olimus

Etymology of TACROLIMUS

The word Tacrolimus is a combination of two parts: tac and rolimus.

The tac portion is derived from Tsukuba Advanced Computing Center - a research institution located in Japan. This institution, abbreviated as TAC, played a significant role in the development and discovery of Tacrolimus.

The rolimus suffix is derived from the name of the compound's class of drugs called macrolides. Macrolides are a group of antibiotics that have a large, macrocyclic lactone ring in their chemical structure. The suffix -rolimus is commonly used to designate drugs that belong to this class.

Therefore, the etymology of the word Tacrolimus reflects the combination of the research institution TAC and the drug class macrolides.