Syphilis hereditaria tarda, also known as late hereditary syphilis, is a medical condition that refers to the late manifestation of syphilis in individuals who were born to mothers with untreated or inadequately treated syphilis during pregnancy. Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum.
Syphilis hereditaria tarda typically occurs in children or young adults, several years after birth. It arises due to the presence of the Treponema pallidum bacteria, which were transmitted from an infected mother to her child during pregnancy or childbirth. This condition may arise if the mother did not receive proper treatment for syphilis before or during pregnancy, or if treatment was only partially effective.
Symptoms of syphilis hereditaria tarda can vary widely and may resemble those of the later stages of acquired syphilis, including the potential involvement of various organs or systems of the body. Common symptoms may include skin lesions, bone abnormalities, enlarged liver and spleen, teeth abnormalities, vision problems, and intellectual disability.
Diagnosis of syphilis hereditaria tarda involves a combination of clinical observation, medical history review, physical examination, and laboratory tests such as blood tests, cerebrospinal fluid analysis, and microscopic examination of tissue samples.
Treatment of syphilis hereditaria tarda typically involves the use of a long-term antibiotic regimen, often including penicillin, to eliminate the Treponema pallidum bacteria. Early and appropriate treatment can greatly improve the prognosis and prevent further complications. Regular follow-up and monitoring are essential to assess the effectiveness of treatment and manage any residual symptoms or long-term complications that may arise.
