SULINDAC Meaning and
Definition
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Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used for its analgesic and anti-inflammatory properties. It belongs to the class of NSAIDs known as arylalkanoic acids and is structurally similar to other drugs in this class, such as indomethacin. Sulindac is primarily used to relieve pain, reduce inflammation, and treat conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
When taken orally, sulindac is rapidly absorbed and metabolized in the liver to its active form, sulindac sulfide. This active metabolite is believed to exert its therapeutic effects by inhibiting the production of prostaglandins, which are mediators of pain and inflammation. Unlike some other NSAIDs, sulindac has a long half-life, allowing for once-daily dosing.
In addition to its anti-inflammatory properties, sulindac has been studied for its potential chemopreventive effects against certain types of cancer, particularly colorectal cancer. It has been shown to inhibit the growth of cancer cells and induce apoptosis, or programmed cell death, in preclinical studies. However, further research is needed to fully understand and utilize these potential anticancer properties.
Like other NSAIDs, sulindac is associated with potential side effects, including gastrointestinal disturbances such as nausea, vomiting, and stomach ulcers. Long-term use may increase the risk of cardiovascular events, including heart attacks and strokes. Therefore, it is important to use sulindac under the supervision of a healthcare professional, carefully considering the potential benefits and risks for each individual patient.
Common Misspellings for SULINDAC
- aulindac
- zulindac
- xulindac
- dulindac
- eulindac
- wulindac
- sylindac
- shlindac
- sjlindac
- silindac
- s8lindac
- s7lindac
- sukindac
- supindac
- suoindac
- sulundac
- suljndac
- sulkndac
- sulondac
- sulindag
Etymology of SULINDAC
The word "sulindac" is derived from a combination of its chemical structure and the suffix "-indac".
The chemical structure of sulindac consists of a sulfide moiety (sul-), which refers to the presence of a sulfur atom, and an indene ring (-ind-), which is a bicyclic aromatic hydrocarbon structure. The suffix "-ac" is a common ending used in organic chemistry for carboxylic acid derivatives.
Thus, when combined, the term "sulindac" denotes a compound that contains a sulfide group along with an indene ring structure and is related to a carboxylic acid derivative.
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