SUBSTITUTED AMPHETAMINE Meaning and
Definition
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A substituted amphetamine refers to a synthetic compound that is structurally related to amphetamine, a central nervous system stimulant. It is a type of psychoactive substance that can have both therapeutic and recreational uses. The term "substituted" in the context of substituted amphetamines suggests that certain groups or atoms have been replaced or added to the amphetamine molecule, resulting in alterations to its chemical structure and pharmacological properties.
These compounds are commonly obtained through modifications to the amphetamine structure, such as adding various substituents to different positions in the molecule. These substitutions typically affect the drug's potency, duration of action, and its affinity for specific receptors in the brain. Substituted amphetamines are often highly lipophilic, meaning they have a strong affinity for fat tissues, which allows them to cross the blood-brain barrier more readily.
The effects of substituted amphetamines can vary depending on the specific compound and the dosage used. They generally produce stimulation of the central nervous system, resulting in increased wakefulness, reduced fatigue, and enhanced focus and concentration. Substituted amphetamines also typically induce euphoria and a sense of heightened energy and self-confidence. Some examples of substituted amphetamines include MDMA (ecstasy), methamphetamine, and methylphenidate (Ritalin).
It is important to note that the use of substituted amphetamines can have potential risks and adverse effects, including increased heart rate, elevated blood pressure, insomnia, anxiety, and addiction. Their recreational use can also lead to dangerous behaviors and long-term health consequences. Therefore, when used medicinally, substituted amphetamines should only be taken under the supervision of a healthcare professional.
Etymology of SUBSTITUTED AMPHETAMINE
The etymology of the term "substituted amphetamine" can be understood by breaking it down into its components:
1. Substituted: The word "substituted" comes from the Latin word "substitutus", which means "put in place of" or "step into the place of". In chemistry, when molecules have one or more atoms replaced by other atoms or groups of atoms, they are considered substituted compounds.
2. Amphetamine: The word "amphetamine" originates from the German word "Amphetamin", which was coined by combining the chemical name "phenylisopropylamine" with "Amphedrin" (a trade name for a similar compound in the 1930s). The original chemical structure of amphetamine was discovered by Romanian chemist Lazăr Edeleanu in 1887.
