The term "Stratum Basale" refers to the deepest layer of the epidermis that is responsible for the regeneration of skin cells. The word "stratum" is derived from the Latin word "stratus," meaning "layer," and "basale" is from "bas-, basis," which means "bottom." The correct pronunciation of "Stratum Basale" is /ˈstreɪtəm bəˈseɪliː/. The stress is on the first syllable of "stratum," and the "a" in "basale" is pronounced as a long "a" sound, as in "day." Proper pronunciation helps in clear communication and understanding of medical terminology.
Stratum basale, also known as the basal layer or germinative layer, is a term used in anatomy and histology to describe the deepest layer of cells in the epidermis, which is the outermost layer of the skin.
The stratum basale is located directly above the dermis and is composed of a single layer of cells that are constantly dividing and replenishing other layers of the epidermis. These cells are known as basal cells or basal keratinocytes. They are cuboidal or columnar in shape and are attached to the basement membrane, which separates the epidermis from the dermis.
The primary function of the stratum basale is to provide continuous renewal of the epidermis. As the basal cells divide, some of the daughter cells migrate upwards towards the surface of the skin, while others remain in the basal layer to maintain its population. The cells that migrate upwards eventually differentiate into different layers of the epidermis and eventually become fully keratinized, providing protection to the underlying tissues.
In addition to basal cells, the stratum basale also contains melanocytes, which are responsible for producing the pigment melanin that gives color to the skin and protects it against harmful ultraviolet (UV) radiation.
Overall, the stratum basale is a crucial layer of the epidermis that plays a vital role in maintaining the integrity and protective function of the skin.
The word "stratum" comes from Latin, where it means "layer" or "level". It is derived from the Latin verb "sternere", meaning "to spread out" or "to stretch". "Basale" also comes from Latin, with its root word being "basal", which means "pertaining to the base". So, combining these two terms, "stratum basale" refers to the base or bottommost layer of a tissue or organ.