SRRSV, also known as Seneca Valley virus (SVV), is a member of the Picornaviridae family that primarily infects pigs. It is a non-enveloped, single-stranded RNA virus with a positive sense genome. The virus was first identified in 2002 and is named after the Seneca Valley, the location in Ohio, United States, where it was initially isolated.
Infection with SRRSV can result in Senecavirus A infection, a disease commonly referred to as "Seneca Valley virus disease" (SVD). SVD is characterized by various clinical signs in pigs, including vesicles and ulcers on the snout, mouth, and hooves, fever, lameness, and anorexia. The disease can lead to significant economic losses in the swine industry due to decreased weight gain, reduced reproduction, and increased mortality.
SRRSV is highly contagious and can spread rapidly within pig populations through direct contact or through contaminated surfaces, feed, or equipment. The virus poses no known risk to humans and has not been associated with food safety concerns.
Currently, there are no specific antiviral treatments available for SRRSV infection, and management practices mainly focus on minimizing the spread of the virus through biosecurity measures, such as quarantine, disinfection, and strict control of pig movement. Vaccination strategies are also being researched to control and prevent SRRSV outbreaks in pig herds.
Overall, SRRSV is an economically significant virus that affects pigs, causing the Seneca Valley virus disease, and preventive measures are crucial in mitigating its impact on the swine industry.
