Sperm Capacitation is the process where the spermatozoa undergoes chemical and physiological changes in the female reproductive tract to acquire the ability to fertilize an egg. The word is spelled as /spɜrm kəˌpæsɪˈteɪʃən/ using the International Phonetic Alphabet (IPA). The first syllable is pronounced as "spɜrm" with an emphasized schwa sound. The second syllable is pronounced as "kəˌpæsɪˈteɪʃən," with the primary stress on the third syllable and secondary stress on the first syllable. The word is commonly used in the field of reproductive biology.
Sperm capacitation is a complex biological process that occurs within the female reproductive tract and is crucial for successful fertilization. It refers to the physiological changes undergone by spermatozoa (sperm cells) in order to acquire the ability to fertilize an egg.
During ejaculation, sperm is released into the female reproductive tract where the seminal fluid provides a supportive environment. However, sperm capacitation involves modifications to the sperm's structure and functionality that allow it to become motile and fully activated for fertilization. This process takes place in the uterus, fallopian tubes, and the final stages occur within the vicinity of the egg.
Sperm capacitation is accompanied by several important changes, including the removal of proteins on the sperm's surface, changes in its plasma membrane, an increase in its intracellular calcium levels, and hyperactivation of its motility. These alterations enable the sperm to effectively penetrate the egg's protective layers and undergo the acrosome reaction – the release of enzymes that dissolve the egg's zona pellucida, facilitating the fusion of sperm and egg membranes.
Sperm capacitation is a highly regulated process influenced by various factors, including the female reproductive tract's biochemistry and hormonal signals. Its successful completion is essential for male fertility and is considered a critical step in achieving successful natural conception or assisted reproductive techniques, such as in vitro fertilization (IVF).
The word "sperm capacitation" comes from Latin and Greek roots.
The term "sperm" originates from the Latin word "sperma", which means "seed". In the context of reproductive biology, "sperm" specifically refers to the male reproductive cells that are involved in fertilization.
The term "capacitation" has its roots in the Latin word "capacitas", meaning "capacity" or "capability". In this context, it refers to the physiological changes that sperm cells undergo, enabling them to fertilize the egg.
Put together, "sperm capacitation" refers to the process by which sperm cells acquire the capability to fertilize an egg, undergoing various changes in their structure and function.