How Do You Spell SPARC GLYCOPROTEIN?

Pronunciation: [spˈɑːk ɡlˈa͡ɪkəpɹˌə͡ʊtiːn] (IPA)

The spelling of the word "SPARC Glycoprotein" may seem daunting, but it's actually quite straightforward once you understand its components. "SPARC" is pronounced /spɑːrk/, with the "a" sound as in "car" and the "r" sound pronounced clearly. "Glycoprotein" is pronounced /ˌɡlaɪkəʊˈprəʊtiːn/, with the "ai" sound as in "buy" and the stress on the second syllable. The prefix "glyco-" indicates that the protein contains sugar molecules. Overall, the spelling of this word follows fairly predictable patterns in English phonetics.

SPARC GLYCOPROTEIN Meaning and Definition

1. SPARC glycoprotein, also known as secreted protein acidic and rich in cysteine, is a type of glycoprotein that is secreted into the extracellular matrix (ECM) or found on the cell surface. It belongs to the matricellular protein family and plays a crucial role in various biological processes, particularly in tissue development, remodeling, and repair.

   The SPARC glycoprotein is characterized by its high content of cysteine residues and its low isoelectric point, which gives it its acidic nature. It is encoded by the SPARC gene and is highly conserved across species. SPARC is primarily found in connective tissues, such as bone, cartilage, blood vessels, and skin, but it is also expressed in various other organs and tissues.

   Functionally, SPARC is involved in a wide range of cellular processes, including cell adhesion, migration, proliferation, and differentiation. It interacts with various ECM components, such as collagen, fibronectin, and integrins, thereby influencing ECM organization and dynamics. Moreover, SPARC can modulate the activity of growth factors and cytokines, acting as a molecular regulator of cell signaling pathways.

   Abnormal SPARC expression has been associated with several pathological conditions, including fibrosis, cancer, and cardiovascular diseases. In cancer, SPARC can have both tumor-suppressive and tumor-promoting effects depending on the context and tumor type.

   In summary, SPARC glycoprotein is an ECM-associated or cell surface glycoprotein that regulates tissue homeostasis and cellular behavior through its interactions with ECM components and modulation of cell signaling pathways.

Common Misspellings for SPARC GLYCOPROTEIN

• aparc glycoprotein
• zparc glycoprotein
• xparc glycoprotein
• dparc glycoprotein
• eparc glycoprotein
• wparc glycoprotein
• soarc glycoprotein
• slarc glycoprotein
• s-arc glycoprotein
• s0arc glycoprotein
• spzrc glycoprotein
• spsrc glycoprotein
• spwrc glycoprotein
• spqrc glycoprotein
• spaec glycoprotein
• spadc glycoprotein
• spafc glycoprotein
• spatc glycoprotein
• spa5c glycoprotein
• spa4c glycoprotein

Etymology of SPARC GLYCOPROTEIN

The word "SPARC Glycoprotein" is derived from an acronym and a scientific term.

1. SPARC: Originally, SPARC stood for "Secreted Protein Acidic and Rich in Cysteine". It was coined in the early 1980s to describe a protein that was found to be highly expressed and secreted by certain cells. Over time, the name SPARC gained widespread recognition and has been used to refer to this specific protein as well as a family of related proteins.

2. Glycoprotein: The term "glycoprotein" is a combination of two words: "glyco-" derived from the Greek word "glykys" meaning sweet or sugar, and "protein" referring to a class of biomolecules that play various roles in living organisms. Glycoproteins are proteins that have sugar molecules (oligosaccharides) attached to them.