The word sophorine is spelled using the phonetic transcription /ˈsɒfəriːn/. The first syllable, "so", is pronounced with a short o sound /ɒ/, the following "pho" is pronounced with an f sound /f/ and a long o sound /əʊ/. The final syllable, "-rine", is pronounced with an r sound /r/ and a long i sound /iː/. Sophorine is a term used in the field of natural products chemistry to refer to a group of alkaloids extracted from certain plants, commonly known as sophora.
Sophorine is a noun that refers to a naturally occurring chemical compound found in various plants, predominantly in legumes. This organic compound belongs to the family of flavonoids, which are known for their diverse biochemical and medicinal properties. Sophorine is specifically derived from the seeds of the Sophora species, such as Sophora japonica and Sophora alopecuroides.
Chemically, sophorine is characterized by its structure that includes a flavonoid skeleton with a substituted piperidine moiety, giving it a distinct molecular configuration. Its physical appearance can range from a crystalline powder to an amorphous solid, depending on the purification process and specific form in which it is isolated.
Sophorine is renowned for its various pharmacological activities, including anti-inflammatory, antioxidant, antimicrobial, and anti-cancer properties. It is often utilized in traditional medicine systems for treating conditions such as inflammation, tumors, and microbial infections. Some studies have also suggested its potential as a chemopreventive agent due to its ability to inhibit cancer cell growth and induce apoptosis.
Furthermore, sophorine's antioxidant properties make it beneficial in combating oxidative stress and protecting against cellular damage caused by free radicals. It has also shown promise as an antimicrobial agent, inhibiting the growth of certain bacteria and fungi.
In conclusion, sophorine is a naturally occurring compound found in plants, particularly legumes, with a range of medicinal properties, including anti-inflammatory, antioxidant, antimicrobial, and potential anti-cancer activities.
An amorphous poisonous alkaloid from Sophora secundiflora and other species of S., probably the same as cytisine, ulexine, and baptitoxine; its salts have been used in migraine and asthma.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.