SNORNA Meaning and
Definition
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SnoRNA, short for small nucleolar RNA, is a type of non-coding RNA molecule that is primarily found in the nucleolus, a sub-compartment within the cell nucleus. It is involved in the processing and modification of other RNA molecules, particularly ribosomal RNA (rRNA).
The primary function of snoRNAs is to guide chemical modifications, such as methylation or pseudouridylation, onto specific nucleotides within rRNA molecules. These modifications are crucial for the proper folding and functioning of rRNA, which is a key component of the ribosome, the cellular machinery responsible for protein synthesis.
SnoRNAs achieve their guidance role through base pairing interactions with the target rRNA molecule. They possess sequence motifs that allow them to recognize and bind to specific sites on the rRNA sequence. Once bound, they recruit necessary enzymes that catalyze the chemical modifications required.
In addition to rRNA, snoRNAs have also been found to participate in the modification of other RNA species, such as small nuclear RNA (snRNA) and transfer RNA (tRNA). They contribute to the fine-tuning of these RNA molecules, influencing their stability, localization, and processing.
Overall, snoRNAs play a significant role in post-transcriptional modification and processing of various RNA molecules within cells. They contribute to the regulation of cellular protein synthesis, and their dysregulation has been associated with certain genetic diseases and cancer. Understanding snoRNAs and their functions provides valuable insights into the complexity of cellular processes and their implications for human health and disease.
Common Misspellings for SNORNA
Etymology of SNORNA
The word "snoRNA" is an acronym that stands for "small nucleolar RNA". The "sno" part refers to "small nucleolar", which describes the size and location of these RNA molecules. They are small in size and primarily found in the nucleolus of the cell. The term was coined in the field of molecular biology to describe a specific group of RNAs involved in RNA modification and processing within the cell.
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