SMG PA PROTEIN Meaning and
Definition
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SMG pA Protein is a term used in molecular biology and genetics to refer to a protein called "Suppressor with Morphology similar to mtnA Gene" or "SMG pA." The SMG pA protein is part of a cellular quality control mechanism involved in mRNA surveillance, which regulates the degradation of messenger RNA (mRNA) molecules.
The SMG pA protein is encoded by the SMG1 gene and is primarily found in eukaryotic organisms, including humans. It plays a crucial role in the nonsense-mediated mRNA decay (NMD) pathway, a process that ensures the elimination of abnormal or prematurely terminated mRNA molecules. In NMD, the SMG pA protein is responsible for identifying and initiating the degradation of faulty mRNA that contains premature stop codons, preventing the translation of truncated and potentially harmful proteins.
The SMG pA protein forms a complex with other proteins, including SMG5, SMG6, and SMG7, to carry out its function. It functions as a serine/threonine kinase, phosphorylating its targets to trigger mRNA degradation. By phosphorylating specific factors involved in the NMD pathway, the SMG pA protein marks the mRNA molecules for degradation by cellular RNA exonucleases.
Overall, the SMG pA protein plays a critical role in maintaining mRNA quality control and ensuring the fidelity of protein synthesis. Its function is essential for normal cellular processes and the prevention of potentially harmful protein products.
Common Misspellings for SMG PA PROTEIN
- amg pa protein
- zmg pa protein
- xmg pa protein
- dmg pa protein
- emg pa protein
- wmg pa protein
- sng pa protein
- skg pa protein
- sjg pa protein
- smf pa protein
- smv pa protein
- smb pa protein
- smh pa protein
- smy pa protein
- smt pa protein
- smg oa protein
- smg la protein
- smg -a protein
- smg 0a protein
- smg pz protein
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