SIDNEY ALTMAN Meaning and
Definition
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Sidney Altman is a distinguished Canadian-American molecular biologist who was awarded the Nobel Prize in Chemistry in 1989 for his groundbreaking discovery of the catalytic properties of RNA molecules. Born on May 7, 1939, in Montreal, Canada, Altman played a vital role in unraveling the essential functions of RNA, a molecule traditionally known for its role in transmitting genetic information.
Altman's research focused on ribonucleic acid (RNA), a molecule that was initially considered only as an intermediate in the flow of genetic information from DNA to proteins. However, Altman demonstrated that RNA molecules can also work as catalysts, capable of triggering chemical reactions. He discovered that RNA could cleave itself at specific locations without the need for any protein enzymes, contradicting the long-held belief that only proteins possessed such catalytic abilities.
This groundbreaking finding, known as RNA self-splicing or catalytic RNA, has significant implications in our understanding of the origins of life and the evolution of genetic systems. Altman's discovery opened up new avenues for research in the field of molecular biology, inspiring scientists to explore RNA's capacity for both storing genetic information and catalyzing essential chemical reactions.
Sidney Altman's contributions to the field of molecular biology have played a crucial role in shaping our understanding of RNA's functions, leading to advances in medical research and the development of novel therapeutic strategies.
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