SIDEROBLAST Meaning and
Definition
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A sideroblast is a type of blood cell characterized by the presence of iron granules in its cytoplasm. The term "sideroblast" is derived from the combination of the Latin word "sidera," meaning iron, and "blast," referring to a developing or immature cell. Sideroblasts are primarily found in the bone marrow, where they undergo development from precursor cells into mature red blood cells.
In a healthy individual, sideroblasts play an essential role in the production of hemoglobin, which is responsible for carrying oxygen throughout the body. Sideroblasts accumulate iron during their development and incorporate it into hemoglobin molecules. This iron deposition leads to the formation of characteristic iron granules, which can be visualized under a microscope.
However, the presence of abnormal sideroblasts can indicate certain blood disorders, such as sideroblastic anemia. In this condition, there is a disruption in the process of iron utilization and incorporation, resulting in an excessive accumulation of iron within the sideroblasts. This abnormal iron distribution can impair the production of functional red blood cells, leading to anemia.
Thus, the identification and evaluation of sideroblasts in blood samples can be significant for diagnosing and monitoring various hematological disorders. Sideroblast count, morphology, and iron deposition pattern are important criteria assessed during laboratory investigations to provide insights into the underlying pathology and guide appropriate treatment strategies.
Common Misspellings for SIDEROBLAST
- aideroblast
- zideroblast
- xideroblast
- dideroblast
- eideroblast
- wideroblast
- suderoblast
- sjderoblast
- skderoblast
- soderoblast
- s9deroblast
- s8deroblast
- siseroblast
- sixeroblast
- siceroblast
- siferoblast
- sireroblast
- sieeroblast
- sidwroblast
Etymology of SIDEROBLAST
The word "sideroblast" is derived from the combination of two Greek roots: "sideros" meaning "iron" and "blastos" meaning "germ" or "bud". The term was coined in the field of medicine to describe abnormally developed red blood cells (erythrocytes) that contain iron deposits.
Similar spelling words for SIDEROBLAST
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