SIALYLTRANSFERASES Meaning and
Definition
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Sialyltransferases are a group of enzymes that play a crucial role in the process of glycosylation, which is the addition of complex sugar molecules to proteins or lipids. These enzymes specifically transfer sialic acid residues from donor molecules to acceptor molecules, leading to the formation of sialylated glycoconjugates.
Sialic acids are a type of negatively-charged sugar molecule that are found at the terminal positions of sugar chains in glycoconjugates. They are involved in various biological processes such as cell adhesion, immune response, and signal recognition. Sialyltransferases are responsible for catalyzing the attachment of sialic acids to glycoproteins, glycolipids, and other sugar chains.
The activity of sialyltransferases is essential for the normal functioning of cells and organisms. They are involved in the development and maintenance of cell and tissue structures, as well as in various physiological processes. Dysregulation or abnormal activity of sialyltransferases has been associated with numerous diseases, including cancers, neurodegenerative disorders, and autoimmune diseases.
Sialyltransferases are classified into different families based on their specific structures and functions. They have been extensively studied due to their significance in glycobiology and their potential as therapeutic targets. Understanding the function and regulation of sialyltransferases is crucial for unraveling the complexities of glycosylation and its implications in various biological processes and diseases.
Common Misspellings for SIALYLTRANSFERASES
- aialyltransferases
- zialyltransferases
- xialyltransferases
- dialyltransferases
- eialyltransferases
- wialyltransferases
- sualyltransferases
- sjalyltransferases
- skalyltransferases
- soalyltransferases
- s9alyltransferases
- s8alyltransferases
- sizlyltransferases
- sislyltransferases
- siwlyltransferases
- siqlyltransferases
- siakyltransferases
- siapyltransferases
- siaoyltransferases
- sialtltransferases
Etymology of SIALYLTRANSFERASES
The word "Sialyltransferases" has its etymology rooted in two main components: "sialyl" and "transferases".
1. Sialyl: The term "sialyl" refers to "sialic acid", which is a type of sugar molecule often found attached to the surface of cells and proteins within the human body. Sialic acid is involved in various biological functions, including cell recognition, signaling, and immune response. The word "sialyl" is derived from the Greek word "sialon", meaning "saliva".
2. Transferases: The suffix "-transferases" refers to a specific class of enzymes in biochemistry. Enzymes ending in "-transferases" are responsible for catalyzing the transfer of functional groups, such as amino acids, lipids, or sugars, from one molecule to another.
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