Serum thymic factor (STF), also known as thymosin fraction V or thymulin, is a peptide hormone found in the thymus gland and blood. It plays a crucial role in the maturation and functioning of T-cells, which are a type of white blood cell involved in the immune response.
STF is produced by the thymus gland, a small organ located in the chest region, and is released into the bloodstream. It acts as a signaling molecule, binding to specific receptors on T-cells and promoting their proliferation and differentiation. This hormone is involved in several immune processes, including the regulation of immune cell migration, activation, and the production of other immune molecules.
The levels of serum thymic factor can vary under different physiological states, such as aging and certain diseases. Decreased levels of STF have been associated with immunodeficiency disorders and autoimmune diseases. Conversely, increased levels of STF have been observed in thymic hyperplasia and certain types of cancer.
Research has shown that the administration of exogenous STF can enhance immune responses and stimulate T-cell development and function. This has led to its potential use as a therapeutic agent for conditions involving immune dysfunction or deficiency.
In summary, serum thymic factor is a hormone produced by the thymus gland that plays a crucial role in the maturation and functioning of T-cells. It acts as a signaling molecule in various immune processes and has therapeutic potential in immune-related disorders.
