SERINE DEHYDRATASE Meaning and
Definition
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Serine dehydratase is an enzyme responsible for the chemical conversion of serine, an amino acid, into pyruvate and ammonia through the process of dehydration. This enzyme plays a critical role in various metabolic pathways, including the biosynthesis of pyruvate, which is a key molecule in energy production and the generation of glucose.
The process of serine dehydration catalyzed by serine dehydratase involves the removal of a water molecule from serine, resulting in the formation of pyruvate. This enzymatic reaction is reversible, and the direction of the reaction depends on the availability of the substrates and the presence of other enzymes or regulatory factors in the metabolic network.
Serine dehydratase is commonly found in bacteria, plants, and animals, and its activity is essential for cellular functioning. Genetic defects or deficiencies in this enzyme can lead to metabolic disorders, such as hereditary serine deficiency or Spinocerebellar ataxia with axonal neuropathy type 2 (SCAN2), which are associated with impaired neurological development and function.
In research and medical fields, understanding the biological mechanisms and regulation of serine dehydratase is crucial for elucidating various physiological processes and developing potential therapeutic strategies for disorders associated with serine metabolism.
Common Misspellings for SERINE DEHYDRATASE
- aerine dehydratase
- zerine dehydratase
- xerine dehydratase
- derine dehydratase
- eerine dehydratase
- werine dehydratase
- swrine dehydratase
- ssrine dehydratase
- sdrine dehydratase
- srrine dehydratase
- s4rine dehydratase
- s3rine dehydratase
- seeine dehydratase
- sedine dehydratase
- sefine dehydratase
- setine dehydratase
- se5ine dehydratase
- se4ine dehydratase
- serune dehydratase
- serjne dehydratase
Etymology of SERINE DEHYDRATASE
The word "serine dehydratase" consists of two components: "serine" and "dehydratase".
1. Serine: The word "serine" comes from the Latin word "sericus", meaning "silk". It was initially isolated from silk protein in 1865 by Swiss chemist Hermann Schardinger. Later in 1878, German chemist Emil Fischer named it "serin" after the silkworm (sericum), as it was extracted from silk fibroin.
2. Dehydratase: The term "dehydratase" is derived from the Latin word "de" (meaning "from" or "away") and the Greek word "hydratos" (meaning "water"). A dehydratase is an enzyme that catalyzes the removal of water molecule(s) during a biochemical reaction.
