SDHD Meaning and
Definition
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SDHD stands for Succinate Dehydrogenase. Succinate Dehydrogenase is an enzyme complex involved in the citric acid cycle, which is also known as the TCA cycle or Krebs cycle. It plays a crucial role in cellular respiration, specifically in the mitochondrial inner membrane.
SDHD is a subunit of the Succinate Dehydrogenase complex. It is an integral membrane protein that binds and oxidizes succinate, facilitating the transfer of electrons to ubiquinone (coenzyme Q). This electron transfer is a crucial step in the electron transport chain, an important process in cellular respiration that produces ATP, the energy currency of cells.
The SDHD gene encodes the protein subunit SDHD, and mutations in this gene can lead to various health conditions, most notably Hereditary Paraganglioma-Pheochromocytoma Syndrome (HPPS). HPPS is a rare genetic disorder characterized by the development of tumors in certain nerve tissues, particularly paraganglia and adrenal glands. These tumors can be benign or malignant and can cause symptoms such as high blood pressure, headaches, and palpitations.
Overall, SDHD is an essential component of the Succinate Dehydrogenase complex, involved in the citric acid cycle and electron transport chain. Understanding its function and mutations in the SDHD gene can provide insights into both normal cellular processes and certain medical conditions.
Common Misspellings for SDHD
- szdhd
- xsdhd
- sxdhd
- sddhd
- sedhd
- sdxhd
- srdhd
- sdrhd
- sdghd
- sdhgd
- sdbhd
- sdhbd
- sdhnd
- sdjhd
- sdhjd
- sduhd
- sdyhd
- sdhyd
- sdhxd
- sdhdx
- sdhdf
- sdhde
- sdhhd
- sdhdd
- s dhd
- sdh d
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