SCHRIDDE GRANULES Meaning and
Definition
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Schridde granules are specialized organelles found in the neurons of the cerebellum, specifically in the granular layer. These granules are named after the German neuroscientist, Hartmut Schridde, who first described them in the 1970s. Functionally, Schridde granules are believed to be involved in the regulation of synaptic transmission within the cerebellar circuit.
Structurally, Schridde granules are tiny, membrane-bound vesicles that contain various proteins and neurotransmitters. They have a diameter of around 0.2 to 0.5 micrometers and are densely packed within the granular layer. These granules have distinct biophysical properties, such as a high concentration of calcium ions, which contribute to their unique function.
Although the exact role of Schridde granules is not fully understood, it is hypothesized that they play a crucial role in regulating synaptic plasticity and neural signaling within the cerebellum. They are thought to be involved in processes such as neurotransmitter release, synaptic vesicle recycling, and modulation of synaptic strength.
Studies have shown that abnormalities in Schridde granules can lead to impairments in cerebellar function and are associated with certain neurological disorders, including ataxias and cerebellar atrophy. Further research is still needed to fully elucidate the precise mechanisms and functions of Schridde granules in normal brain function and disease states.
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A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
Common Misspellings for SCHRIDDE GRANULES
- achridde granules
- zchridde granules
- xchridde granules
- dchridde granules
- echridde granules
- wchridde granules
- sxhridde granules
- svhridde granules
- sfhridde granules
- sdhridde granules
- scgridde granules
- scbridde granules
- scnridde granules
- scjridde granules
- scuridde granules
- scyridde granules
- scheidde granules
- schdidde granules
- schfidde granules
- schtidde granules
