The word "schizocyte" refers to an abnormal red blood cell that has divided into fragments. Its spelling can be a bit tricky, but the IPA phonetic transcription can help clarify it: /ˈskɪzoʊˌsaɪt/. The first part of the word, "schizo," is pronounced with a hard "s" sound followed by a "k" sound. The second part, "cyte," is pronounced with a long "i" sound and a hard "t" sound. Altogether, "schizocyte" is pronounced skiz-oh-sahyt.
A schizocyte is a term used in hematology to describe a type of red blood cell (RBC) found in the bloodstream, characterized by abnormal shape or morphology. The word "schizocyte" is derived from the Greek words "schizo," meaning to split or divide, and "cyte," meaning cell. This term refers to the splitting or fragmentation of the RBC, resulting in irregular or fragmented shapes.
Schizocytes are commonly observed in various medical conditions, particularly those associated with hematological disorders or mechanical trauma to the blood vessels. These abnormalities in shape can occur due to different mechanisms, including shearing forces, oxidative stress, or the activation of various enzymes within the bloodstream. Schizocytes are often identified and quantified through microscopic examination of a blood smear.
The presence of schizocytes in the blood can have clinical significance as it may indicate an underlying medical condition. Conditions associated with schizocytes include disseminated intravascular coagulation (DIC), thrombotic thrombocytopenic purpura (TTP), hemolytic uremic syndrome (HUS), and certain mechanical heart valve prostheses.
The identification of schizocytes in a patient's blood may prompt further investigation and diagnostic tests to determine the underlying cause. Treatment strategies for conditions associated with schizocytes often focus on managing the underlying condition, such as addressing the underlying coagulation disorder or removing the source of mechanical trauma. In severe cases, interventions such as blood transfusions or surgical interventions may be necessary.
Schistocyte.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word schizocyte is derived from two Greek terms: schizo meaning to split or to cleave, and cyte meaning cell.