How Do You Spell RUSSELL VIPER VENOM TIME?

Pronunciation: [ɹˈʌsə͡l vˈa͡ɪpə vˈɛnəm tˈa͡ɪm] (IPA)

The spelling of the word "Russell Viper Venom Time" is a mouthful. Let's break it down using IPA phonetic transcription. "Russell" is pronounced as /ˈrʌsəl/. "Viper" is pronounced as /ˈvaɪ.pər/. "Venom" is pronounced as /ˈvɛnəm/. And finally, "Time" is pronounced as /taɪm/. All together, the word is pronounced as /ˈrʌsəl ˈvaɪ.pər ˈvɛnəm taɪm/. It refers to the period of time it takes for the venom of a Russell's viper to coagulate blood, which is used as a diagnostic test for clotting disorders.

RUSSELL VIPER VENOM TIME Meaning and Definition

1. Russell Viper Venom Time, also known as RVVT, is a laboratory test that measures the time taken for blood to clot in response to the venom of the Russell's viper snake (Daboia russelii). This test is commonly used to assess the presence of an abnormal clotting factor in a person's blood, often as an indication of certain autoimmune disorders, such as lupus anticoagulant.

   To conduct the Russell Viper Venom Time test, a patient's blood is collected and mixed with a small amount of Russell's viper venom. The venom contains enzymes that activate the coagulation process in blood. The time required for the blood to form a clot is then measured and compared to the average clotting time of a normal individual. If the clotting time is significantly prolonged compared to the control, it may suggest the presence of an abnormal clotting factor.

   The Russell Viper Venom Time test is used in conjunction with other tests, such as the activated partial thromboplastin time (APTT) and prothrombin time (PT), to diagnose and monitor clotting disorders. It helps to identify conditions like antiphospholipid syndrome, which can increase the risk of abnormal blood clotting and vascular diseases.

   It is important to note that the RVVT test is not a definitive diagnosis, but rather a screening tool that assists healthcare providers in determining if further investigation is required. A positive result may prompt additional testing, such as specific factor assays or lupus anticoagulant confirmatory tests, to accurately diagnose the underlying disorder.

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