How Do You Spell RILUZOLE?

Pronunciation: [ɹˈɪluːzˌə͡ʊl] (IPA)

The word "Riluzole" is used to describe a drug commonly used to treat amyotrophic lateral sclerosis (ALS). The spelling of this word can be confusing due to its unusual combination of letters. However, understanding the pronunciation can make it easier to remember. The word is pronounced as /ˈrɪluːzoʊl/, with emphasis on the second syllable. The "Ri" is pronounced like "ree," while the "lu" and "zo" sections are pronounced as expected. The "le" at the end of the word is silent.

RILUZOLE Meaning and Definition

1. Riluzole is a pharmaceutical drug used primarily to treat a neurological disorder known as amyotrophic lateral sclerosis (ALS), also referred to as Lou Gehrig's disease. It falls under the category of a glutamate antagonist, meaning it works by inhibiting the release of a neurotransmitter called glutamate in the brain. Glutamate is known to be excessively released in individuals with ALS, leading to the death of motor neurons.

   The primary mode of action of riluzole involves blocking voltage-dependent sodium channels, thereby reducing the electrical activity and release of glutamate. By doing so, riluzole helps to slow down the progression of ALS symptoms, particularly in terms of muscle function and movement.

   In addition to its effects on glutamate, riluzole also possesses antioxidant properties, which may contribute to its neuroprotective effects. These antioxidant properties enable riluzole to combat oxidative stress, a condition where there is an imbalance between the production of harmful free radicals and the body's ability to neutralize them.

   Common side effects associated with riluzole include nausea, vomiting, dizziness, and gastrointestinal disturbances. Due to its potential interactions with other medications and its impact on liver function, cautious monitoring is typically required while taking riluzole.

   Although riluzole cannot cure ALS, it has been determined to be effective in extending the survival rate and slowing down the progression of the disease. As such, it has become a standard part of the treatment regimen for individuals diagnosed with ALS.

Common Misspellings for RILUZOLE

• eiluzole
• diluzole
• filuzole
• tiluzole
• 5iluzole
• 4iluzole
• ruluzole
• rjluzole
• rkluzole
• roluzole
• r9luzole
• r8luzole
• rikuzole
• ripuzole
• riouzole
• rilyzole
• rilhzole
• riljzole
• rilizole
• ril8zole

Etymology of RILUZOLE

The word "Riluzole" is derived from French and a combination of two words. It comes from the French "riluzol", which is a variation of "riluzole", coined by the pharmaceutical company Rhône-Poulenc in the late 1980s. The second part of the word, "-azole", is a common suffix used in chemistry to designate a class of organic compounds.