RICIN B CHAIN Meaning and
Definition
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The term "Ricin B Chain" refers to the B-chain component of ricin, a highly potent protein toxin derived from the seeds of the castor oil plant (Ricinus communis). Ricin is considered one of the most toxic substances known to mankind.
The B-chain is one of the two subunits that make up the ricin toxin, the other being the A-chain. The B-chain is responsible for the specific binding and internalization of ricin into cells. It is a lectin, which means it has an affinity for specific sugar molecules found on the surface of cells. The B-chain specifically recognizes and binds to galactose residues present on the glycoproteins of cell membranes.
Once the B-chain binds to the galactose residues on the cell surface, it allows the A-chain to enter the cell through receptor-mediated endocytosis. Inside the cell, the A-chain separates from the B-chain and undergoes further processing to exert its toxic effects. The A-chain inhibits protein synthesis by damaging the ribosomes, leading to cell death.
In conclusion, the Ricin B Chain is the subunit of ricin toxin responsible for binding and internalization into cells. It possesses lectin activity and recognizes galactose residues on cell membranes, enabling the toxin to enter cells via receptor-mediated endocytosis. It plays a crucial role in facilitating the delivery and subsequent toxicity of ricin within targeted cells.
Common Misspellings for RICIN B CHAIN
- eicin b chain
- dicin b chain
- ficin b chain
- ticin b chain
- 5icin b chain
- 4icin b chain
- rucin b chain
- rjcin b chain
- rkcin b chain
- rocin b chain
- r9cin b chain
- r8cin b chain
- rixin b chain
- rivin b chain
- rifin b chain
- ridin b chain
- ricun b chain
- ricjn b chain
- rickn b chain
- ricon b chain
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