Pronunciation: [ɹˈɛd sˈɒfənɪŋ ɒvðə bɹˈe͡ɪn] (IPA) 
Correct spelling for the English word "red softening of the brain" is [ɹˈɛd sˈɒfənɪŋ ɒvðə bɹˈe͡ɪn], [ɹˈɛd sˈɒfənɪŋ ɒvðə bɹˈeɪn], [ɹ_ˈɛ_d s_ˈɒ_f_ə_n_ɪ_ŋ ɒ_v_ð_ə b_ɹ_ˈeɪ_n] (IPA phonetic alphabet).
Red softening of the brain, medically known as encephalomalacia, is a pathological condition characterized by the softening and reddening of brain tissue. It refers to the degeneration and death of brain cells due to a lack of sufficient blood supply or impaired blood flow to the affected area. This condition can be caused by a variety of factors, including cerebral ischemia (restriction of blood flow), cerebral hemorrhage (bleeding within the brain), traumatic brain injury, infection, or certain diseases.
The term "red" in red softening of the brain refers to the color change that occurs as a result of hypoxic (oxygen deficiency) conditions within the damaged brain tissue. The inadequate blood supply leads to a decrease in oxygen and nutrient delivery to the affected brain region, causing cellular death and subsequent softening. As a result, the tissue may appear reddish due to the accumulation of blood in the area or the breakdown of blood cells.
The symptoms of red softening of the brain can vary depending on the extent and location of the brain damage, but typically include neurological impairments such as cognitive dysfunction, motor deficits, speech difficulties, and sensory disturbances. Treatment for this condition focuses on addressing the underlying causes, such as managing blood pressure, preventing infections, or providing supportive care and therapy to improve neurological function.
In summary, red softening of the brain is a pathological condition characterized by the softening and reddening of brain tissue due to insufficient blood supply. It can result from various causes and leads to the degeneration of brain cells, causing neurological impairments.
The primary congestive stage of acute suppurative encephalitis.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
