RECOMBINANT G CSF Meaning and
Definition
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Recombinant Granulocyte Colony-Stimulating Factor (G CSF) is a term used in the field of biotechnology and medicine. It refers to a genetically engineered form of a naturally occurring hormone called granulocyte-colony stimulating factor.
G CSF is primarily produced by the body to stimulate the production and maturation of a specific type of white blood cells called neutrophils in the bone marrow. These neutrophils play a vital role in the human immune system, as they are the first responders in fighting bacterial and fungal infections.
Recombinant G CSF is created by using recombinant DNA technology, where the gene responsible for producing the hormone is isolated and inserted into a host organism, usually bacteria or yeast. These genetically modified organisms are then cultured in special laboratory conditions, allowing them to produce and secrete large quantities of the recombinant G CSF protein.
The recombinant G CSF is then collected, purified, and formulated into a medication that can be administered to patients. It is often used in clinical settings to help stimulate the production of neutrophils in individuals with weakened immune systems, such as those undergoing chemotherapy or bone marrow transplantation.
Overall, recombinant G CSF is a valuable therapeutic tool in modern medicine, helping to boost the immune response and prevent infections in patients at high risk.
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