How Do You Spell QUISQUALATE RECEPTORS?

Pronunciation: [kwˈɪskwəlˌe͡ɪt ɹɪsˈɛptəz] (IPA)

Quisqualate receptors are a type of ionotropic glutamate receptor found in the brain. The spelling of this word can be explained using the International Phonetic Alphabet (IPA). The first syllable, "kwɪs-", is pronounced with a voiceless palatal stop followed by a short "i" vowel sound. The second syllable, "-kwəleɪt", is pronounced with a voiced alveolar fricative and a schwa sound, ending with a long "eɪ" diphthong. The final syllable, "-rɛsɛptərz", is pronounced with an unvoiced alveolar fricative and a schwa sound, ending with a distinct "z" sound.

QUISQUALATE RECEPTORS Meaning and Definition

1. Quisqualate receptors are a subtype of receptors known as metabotropic glutamate receptors (mGlus). They are named after the compound quisqualate, which is a synthetic analog of a glutamate-like molecule, and they have a high affinity for this compound. Quisqualate receptors are widely distributed throughout the central nervous system and play a crucial role in various neuronal functions.

   These receptors belong to the G-protein coupled receptor family and are classified into three subtypes, namely Group I, Group II, and Group III, based on their pharmacological properties and signaling mechanisms. The Group I receptors include mGlu1 and mGlu5, whereas the Group II receptors consist of mGlu2 and mGlu3, and the Group III receptors comprise mGlu4, mGlu6, mGl7, and mGlu8.

   Activation of quisqualate receptors leads to the modulation of synaptic transmission and neuronal excitability. They are primarily involved in the regulation of neurotransmitter release, synaptic plasticity, and neuronal development. Quisqualate receptors also play a significant role in the pathophysiology of several neurological disorders, including neurodegenerative diseases, epilepsy, and psychiatric disorders.

   Selective modulation of quisqualate receptors has been shown to have therapeutic potential for the treatment of various neurological conditions. Therefore, understanding the function and signaling pathways of these receptors is crucial for the development of novel therapeutic interventions targeting the glutamate system.

Common Misspellings for QUISQUALATE RECEPTORS

• 1uisqualate receptors
• 2uisqualate receptors
• wuisqualate receptors
• auisqualate receptors
• qyisqualate receptors
• qhisqualate receptors
• qjisqualate receptors
• qiisqualate receptors
• q8isqualate receptors
• q7isqualate receptors
• quusqualate receptors
• qujsqualate receptors
• quksqualate receptors
• quosqualate receptors
• qu9squalate receptors
• qu8squalate receptors
• quiaqualate receptors
• quizqualate receptors
• quixqualate receptors
• quidqualate receptors

Etymology of QUISQUALATE RECEPTORS

The etymology of the word "quisqualate" originates from the compound of "quisqu-", meaning something uncertain or doubtful, and "-alate", referring to its similarity or connection with something else. The term "quisqualate" was coined to describe a compound that was structurally similar to kainic acid, an excitatory amino acid found in certain seaweeds.

The word "receptors" is derived from the Latin word "receptor", meaning a receiver or a device that receives signals or stimuli. In the context of biology and neuroscience, receptors are proteins that bind specific molecules, such as neurotransmitters or hormones, and trigger cellular responses.

Therefore, "quisqualate receptors" refers to a type of receptors present in the nervous system that bind with the compound quisqualate, which can activate certain cellular responses or synaptic events.