QUINAZOLINE Meaning and
Definition
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Quinazoline is a chemical compound and a heterocyclic aromatic organic compound. It is classified as a bicyclic compound, consisting of a benzene ring fused with a pyrimidine ring. The chemical formula of quinazoline is C8H6N2, and it has a molecular weight of 130.15 grams per mole.
Quinazoline is a versatile compound that finds applications in various fields, including medicinal chemistry and drug development. Many quinazoline derivatives have been synthesized and studied for their potential biological activities. Some of these derivatives have demonstrated significant pharmacological properties, such as anti-cancer, anti-microbial, anti-inflammatory, and anti-viral activities. These properties make quinazoline an important scaffold for the development of therapeutic agents.
In terms of its physical properties, quinazoline appears as a colorless solid in its pure form, although it can have a yellowish appearance due to impurities. It has a melting point of around 42-45 degrees Celsius and is sparingly soluble in water.
The synthesis of quinazoline compounds involves various methods, including condensation reactions between anthranilic acid derivatives and carbonyl compounds. These synthetic methodologies allow for the preparation of a wide range of quinazoline derivatives with different substituents on the benzene and pyrimidine rings, enabling structure-activity relationship studies for drug discovery purposes.
Overall, quinazoline is a significant compound in the field of organic chemistry and pharmaceutical research, due to its diverse range of biological activities and potential applications in drug development.
Common Misspellings for QUINAZOLINE
- 1uinazoline
- 2uinazoline
- wuinazoline
- auinazoline
- qyinazoline
- qhinazoline
- qjinazoline
- qiinazoline
- q8inazoline
- q7inazoline
- quunazoline
- qujnazoline
- quknazoline
- quonazoline
- qu9nazoline
- qu8nazoline
- quibazoline
- quimazoline
- quijazoline
- quihazoline
Etymology of QUINAZOLINE
The etymology of the word "quinazoline" can be traced back to the chemical structure of the compound. It is derived from two components: "quinazol" and "ine".
The term "quinazol" derives from the combination of "quinoline" and "pyrazole". Quinoline is a heterocyclic compound with a seven-membered aromatic ring consisting of five carbon atoms and one nitrogen atom. It is commonly found in various natural products and alkaloids.
On the other hand, "ine" is a commonly used suffix in organic chemistry that is often attached to nitrogen-containing compounds. It is derived from the German word "ammoniak" and indicates the presence of an amine functional group (-NH2) in the molecule.
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