Pronunciation: [kwˈasa͡ɪn] (IPA) 
The word "Quassine" is a complex word with confusing spelling. In IPA transcription, it is pronounced as /kwəˈsiːn/. The "q" is pronounced as "kw," and the first "s" is silent, leaving only the second "s" to be pronounced. The "i" is pronounced as "ee," and the final "ne" is pronounced as "n." This word is commonly used in medicine and refers to a bitter substance found in the bark of a tree used for medicinal purposes.
Quassine is a noun that refers to a bitter compound derived from the bark of the Quassia tree. It belongs to a class of compounds called quassinoids, which are known for their pronounced bitterness and medicinal properties. Quassine is primarily found in the species Quassia amara, native to the tropical regions of South America and the Caribbean.
In traditional medicine, Quassine has been used for its therapeutic properties, particularly as a potent antiparasitic agent. It is known to exhibit strong vermifugal (worm-expelling) activity and has been traditionally employed for treating various parasitic infections, such as malaria, tapeworms, and threadworms. Quassine is believed to work by disrupting the reproductive processes of the parasites, thereby preventing their proliferation and survival.
Apart from its antiparasitic properties, Quassine has also been studied for its potential anti-inflammatory, anticancer, and immune-stimulatory effects. Researchers have explored its use in managing inflammatory conditions, including arthritis and allergies. Additionally, preliminary studies suggest that Quassine may possess anticancer activities by impeding the growth of cancer cells and inducing apoptosis (programmed cell death).
The bitterness of Quassine has also made it a popular ingredient in the food and beverage industry. It is occasionally used to enhance the flavor of certain beverages, such as bitters and tonics. In these applications, Quassine provides a distinctive and memorable bitter taste.
Overall, Quassine is a bitter compound derived from the Quassia tree, known for its antiparasitic, anti-inflammatory, anticancer, and immune-stimulatory properties. Its varied medicinal applications and potential culinary uses make it a compound of interest in the fields of pharmacology and food science.
The bitter principle of quassia.
Etymological and pronouncing dictionary of the English language. By Stormonth, James, Phelp, P. H. Published 1874.
The word "Quassine" can be traced back to the root word "quassia". "Quassia" is derived from the name of the African herbalist, Quassi, who first discovered the medicinal properties of the bark of the tree.
