The word "quadrune" refers to a person with one-fourth black ancestry, often used in a derogatory manner. The correct pronunciation of "quadrune" is [kwɑːdruːn], with the stress on the first syllable. The "qua" sound is pronounced as "kw", while the "drune" sounds like "druun". This word is commonly misspelled as "quadroon" or "quadruon", but the correct spelling is "quadrune". However, it's important to note that this word is considered offensive and racially derogatory, and should not be used in modern language.