PYRROLIDINONES Meaning and
Definition
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Pyrrolidinones are a class of organic chemical compounds that consist of a five-membered lactam ring, specifically a pyrrolidin-2-one (also known as a pyrrolidone) ring. These compounds are derived from pyrrolidine, an organic compound that contains a five-membered nitrogen-containing ring.
Pyrrolidinones are characterized by the presence of a carbonyl group (C=O) within the lactam ring, which imparts its own unique chemical and functional properties to these compounds. The carbonyl group is responsible for enabling various chemical reactions, such as nucleophilic addition, condensation, and reduction, which contribute to the versatility of pyrrolidinones as key building blocks for the synthesis of numerous pharmaceutically active compounds and other organic molecules.
Due to their structural features and diverse chemical reactivity, pyrrolidinones find applications in various fields, including drug discovery, medicinal chemistry, and materials science. Their ability to readily undergo various transformations allows chemists to create diverse arrays of pyrrolidinone derivatives with tailored properties and functionalities.
In the pharmaceutical industry, pyrrolidinones have been extensively explored as core scaffolds for developing therapeutically important molecules. Their unique structural characteristics offer opportunities for designing compounds with desired biological activities, enhancing drug-like properties, and optimizing pharmacokinetic profiles.
Overall, pyrrolidinones play a crucial role in organic synthesis, drug development, and material science, making them important compounds in various scientific disciplines.
Common Misspellings for PYRROLIDINONES
- oyrrolidinones
- lyrrolidinones
- -yrrolidinones
- 0yrrolidinones
- ptrrolidinones
- pgrrolidinones
- phrrolidinones
- purrolidinones
- p7rrolidinones
- p6rrolidinones
- pyerolidinones
- pydrolidinones
- pyfrolidinones
- pytrolidinones
- py5rolidinones
- py4rolidinones
- pyreolidinones
- pyrdolidinones
- pyrfolidinones
- pyrtolidinones
Etymology of PYRROLIDINONES
The word "pyrrolidinones" can be broken down into two parts: "pyrrolidin" and "ones".
The term "pyrrolidin" is derived from "pyrrolidine", which refers to a saturated heterocyclic organic compound. The term "pyrrolidine" itself comes from the combination of "pyrrole" and the suffix "-idine".
"Pyrrole" is a nitrogen-containing aromatic compound that was first isolated from crude oil in 1834 by Danish chemist Christian Friederich Emil Hornemann. The name "pyrrole" is said to be derived from the Greek word "pyrrhos", meaning "reddish" or "flame-colored", referring to the compound's reddish-brown appearance when oxidized.
The suffix "-idine" is a common ending used for many chemical compounds that belong to the class of pyridine-related compounds.
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