Pyronyxis is a word that is difficult to spell, even for experienced writers. In phonetic transcription, it is pronounced as /paɪrəʊˈnɪksɪs/. The first syllable ‘pyr’ is pronounced like ‘fire’ with a long ‘i’ sound. The second syllable ‘o’ is pronounced like the letter ‘o’ in ‘only’. The third and fourth syllables ‘nyxi’ are pronounced as ‘nik-sis’ with a short ‘i’ sound. Finally, the last syllable ‘s’ is pronounced as the letter ‘s’ in ‘sun’. With all of these sounds combined, pyronyxis is a challenging word to spell and pronounce accurately.
Ignipuncture.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.