PVEGF Meaning and
Definition
-
PVEGF, also known as Placental Vascular Endothelial Growth Factor, is a protein that plays a crucial role in the development and maintenance of blood vessels within the placenta during pregnancy. It belongs to the family of vascular endothelial growth factors (VEGFs), which are responsible for promoting angiogenesis, a process that involves the growth of new blood vessels from existing ones.
PVEGF is specifically expressed in the placenta and exerts its effects by binding and activating VEGF receptors that are present on the surface of endothelial cells. Once activated, these receptors initiate a cascade of events that stimulate the growth and proliferation of endothelial cells, leading to the formation and remodeling of blood vessels.
The role of PVEGF is fundamental for ensuring adequate blood supply to the developing fetus, as it facilitates the exchange of oxygen and nutrients between the maternal and fetal circulation. It also plays a crucial role in maintaining the structural integrity of the placenta and preventing complications such as preeclampsia, a condition characterized by high blood pressure and damage to organs.
Abnormalities in PVEGF expression or function have been associated with various pregnancy disorders, including intrauterine growth restriction and placental insufficiency. Therefore, understanding the mechanisms underlying PVEGF regulation and its interactions with other factors involved in placental development is of great importance for the field of reproductive biology and may have implications for the diagnosis and treatment of pregnancy-related complications.
Common Misspellings for PVEGF
- lvegf
- 0vegf
- pbegf
- pgegf
- pvwgf
- pvsgf
- pvrgf
- pv4gf
- pv3gf
- pvehf
- pveyf
- pvegd
- pvegv
- pvegg
- pvegt
- pvegr
- opvegf
- povegf
- lpvegf
- p-vegf
Infographic
Add the infographic to your website:
