Purohepatitis is a medical term that refers to inflammation of the liver parenchyma. The word "purohepatitis" is derived from the Greek words "pur" meaning "pus," "hepar" meaning "liver," and "itis" meaning "inflammation." The condition is characterized by the presence of pus within the liver tissue, leading to swelling, pain, and dysfunction of the organ.
Purohepatitis may result from various causes, including bacterial or fungal infections, such as pyogenic liver abscess or amoebic liver abscess. In some cases, it may be a complication of an underlying condition such as liver cirrhosis or immune system disorders. The presence of pus within the liver can lead to liver cell damage, impairment of liver function, and potential spread of infection to other parts of the body.
Common symptoms of purohepatitis include abdominal pain, fever, fatigue, jaundice, and loss of appetite. Diagnosis typically involves a combination of medical history evaluation, physical examination, blood tests, imaging studies like ultrasound, CT scan, or MRI, and sometimes a liver biopsy.
Treatment for purohepatitis aims at addressing the underlying cause and managing the symptoms. It may include antibiotic or antifungal medications to control the infection, drainage of pus through either percutaneous or surgical means, and supportive care to relieve symptoms and promote liver recovery. In severe cases, surgery may be necessary to remove infected areas or manage complications.
Prognosis for purohepatitis depends on the cause, extent of liver damage, and timely and appropriate treatment. Early detection, prompt medical intervention, and proper management are crucial in improving outcomes and preventing further complications.
