How Do You Spell PROTHROMBASE?

Pronunciation: [pɹˈɒθɹəmbˌe͡ɪs] (IPA)

Prothrombase is a medical term used to describe a blood plasma glycoprotein that is involved in blood clotting. The word is spelled with a long "o" sound and is pronounced \prō-ˈthräm-ˌbās\. The sound "pr" at the beginning is pronounced with a soft "p" followed by an "r." The following "o," "th," "r," "o," "m," and "b" sounds are pronounced similar to their respective letter sounds. The "a" in the end is pronounced with a long "a" sound followed by an "s" with a soft "s" sound.

PROTHROMBASE Meaning and Definition

1. Prothrombase is a term commonly used in the field of medicine and specifically in the study of blood clotting. It refers to a protein known as thrombin, which plays a crucial role in the coagulation of blood.

   Thrombin is a serine protease enzyme that is involved in the final steps of the blood clotting cascade. It is derived from its inactive precursor form, prothrombin. Prothrombin is synthesized in the liver and released into the bloodstream, where it is eventually activated by a complex series of enzymatic reactions.

   The activation of prothrombin to thrombin is a crucial step in the blood clotting process. Once activated, thrombin acts as an enzyme and catalyzes the conversion of fibrinogen, a soluble protein, into fibrin, an insoluble protein. Fibrin molecules then come together to form a mesh-like network, essentially creating a blood clot that helps stop bleeding.

   The role of prothrombase in the blood clotting process makes it an essential component of the body's hemostasis mechanism. Abnormalities in prothrombin can lead to various coagulation disorders and can put individuals at an increased risk of bleeding or thrombosis.

   Overall, prothrombase is a protein that plays a critical role in blood clotting, ensuring the body's ability to maintain hemostasis and prevent excessive bleeding.

2. Prothrombin.

   A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

Common Misspellings for PROTHROMBASE

• orothrombase
• lrothrombase
• -rothrombase
• 0rothrombase
• peothrombase
• pdothrombase
• pfothrombase
• ptothrombase
• p5othrombase
• p4othrombase
• prithrombase
• prkthrombase
• prlthrombase
• prpthrombase
• pr0thrombase
• pr9thrombase
• prorhrombase
• profhrombase
• proghrombase
• proyhrombase

Etymology of PROTHROMBASE

The word "prothrombase" appears to be a combination of two terms: "prothrombin" and "ase".

- "Prothrombin" is a protein that plays a crucial role in the formation of blood clots. It is produced in the liver and is converted to thrombin in the clotting process. The word "prothrombin" originates from the Greek roots "pro" meaning "before" or "in front of", and "thrombōsis" meaning "clotting".

- "Ase", as a suffix, generally denotes an enzyme or protein. It derives from the Latin "asum", which signifies "pertaining to" or "having the nature of".

Therefore, "prothrombase" can be inferred to refer to an enzyme or protein related to prothrombin, which is involved in the clotting mechanism.