PROPERDIN FACTOR D Meaning and
Definition
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Properdin Factor D is a protein that plays a crucial role in the human immune system. It is an essential component of the alternative pathway of the complement system, which is responsible for identifying and eliminating foreign pathogens from the body. Properdin Factor D acts as an enzyme, catalyzing the cleavage of a specific peptide bond in an inactive precursor protein called properdin Factor P, thereby activating it.
Once activated, properdin Factor P interacts with other complement proteins to form a complex known as the properdin C3 convertase. This complex initiates a cascade of biochemical reactions, leading to the formation of the membrane attack complex (MAC), which can directly destroy microorganisms.
Properdin Factor D is primarily synthesized in the liver and is present in the bloodstream. It is continuously produced to maintain an appropriate level of complement activity, ensuring an effective immune response against infections.
Deficiencies or dysregulation in Properdin Factor D can affect the proper functioning of the alternative complement pathway, leading to an increased susceptibility to infections or an overactive immune response. In some cases, mutations in the corresponding gene coding for Properdin Factor D can result in hereditary properdin deficiency, a rare condition that can lead to recurrent infections and autoimmune disorders.
Understanding the role and function of Properdin Factor D is important for biomedical research and may have implications for the development of novel therapeutic strategies to modulate the immune response and combat various diseases.
Common Misspellings for PROPERDIN FACTOR D
- prioperdin factor b
- oroperdin factor d
- lroperdin factor d
- -roperdin factor d
- 0roperdin factor d
- peoperdin factor d
- pdoperdin factor d
- pfoperdin factor d
- ptoperdin factor d
- p5operdin factor d
- p4operdin factor d
- priperdin factor d
- prkperdin factor d
- prlperdin factor d
- prpperdin factor d
- pr0perdin factor d
- pr9perdin factor d
- prooerdin factor d
- prolerdin factor d
- pro-erdin factor d
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