How Do You Spell PROLINE DEHYDROGENASE?

Pronunciation: [pɹˈɒliːn dˌiːha͡ɪdɹˈə͡ʊd͡ʒne͡ɪs] (IPA)

Proline Dehydrogenase is a scientific term that refers to an enzyme important in the metabolism of amino acids. The word can be broken down into its individual phonemes, which can be transcribed using the International Phonetic Alphabet (IPA) as [pɹoʊlin diːhaɪdɹoʊdʒɪnəs]. The initial "p" is pronounced with a puff of air, following by the vowel sounds "oʊ" and "i". The middle syllable includes a long "ee" sound, and the final syllable features the "dʒ" sound as in "judge".

PROLINE DEHYDROGENASE Meaning and Definition

1. Proline dehydrogenase is a type of enzyme that plays a crucial role in the metabolism of the amino acid proline. It is an oxidoreductase enzyme that catalyzes the conversion of proline to pyrroline-5-carboxylate. This reaction involves the oxidation of proline and the transfer of electrons to an electron acceptor, typically FAD (flavin adenine dinucleotide).

   Proline dehydrogenase is found in various organisms, including bacteria, yeast, plants, and animals. It is particularly important in the maintenance of cellular homeostasis and energy metabolism. By converting proline to pyrroline-5-carboxylate, this enzyme participates in the tricarboxylic acid (TCA) cycle, also known as the citric acid cycle or Krebs cycle. Through this cycle, pyrroline-5-carboxylate can be further metabolized to yield ATP, the primary energy currency of cells.

   Furthermore, proline dehydrogenase is involved in the regulation of cellular redox balance. It helps maintain proper levels of reactive oxygen species (ROS) and reactive nitrogen species (RNS) within cells, which are crucial for various cellular processes such as signal transduction, gene expression, and immune response.

   Deficiencies or abnormalities in proline dehydrogenase activity have been associated with certain diseases and conditions, including neurodegenerative disorders, cancer, and metabolic disorders. Studying the function and regulation of proline dehydrogenase can provide valuable insights into these pathological conditions and potentially contribute to the development of therapeutic interventions.

Common Misspellings for PROLINE DEHYDROGENASE

• oroline dehydrogenase
• lroline dehydrogenase
• -roline dehydrogenase
• 0roline dehydrogenase
• peoline dehydrogenase
• pdoline dehydrogenase
• pfoline dehydrogenase
• ptoline dehydrogenase
• p5oline dehydrogenase
• p4oline dehydrogenase
• priline dehydrogenase
• prkline dehydrogenase
• prlline dehydrogenase
• prpline dehydrogenase
• pr0line dehydrogenase
• pr9line dehydrogenase
• prokine dehydrogenase
• propine dehydrogenase
• prooine dehydrogenase
• prolune dehydrogenase

Etymology of PROLINE DEHYDROGENASE

The word "proline" in the term "Proline Dehydrogenase" comes from the amino acid proline, which is the substrate on which this enzyme acts. The term "dehydrogenase" is derived from "dehydrogenation", which refers to the removal of hydrogen atoms from a molecule. Hence, "Proline Dehydrogenase" describes an enzyme that catalyzes the removal of hydrogen from proline.