PRE MRNA Meaning and
Definition
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Pre-mRNA, also known as precursor mRNA, refers to the initial transcript produced during transcription of a gene in eukaryotic cells. It is a primary RNA molecule that is synthesized in the nucleus before undergoing several modifications to become mature mRNA. Pre-mRNA contains both exons, which are the coding regions of a gene, and introns, which are non-coding regions that are removed during RNA processing.
The transcription of a gene begins with the binding of RNA polymerase to the DNA template strand, resulting in the synthesis of a pre-mRNA molecule. This pre-mRNA undergoes several processes such as capping, splicing, and polyadenylation to produce the mature mRNA molecule that can be translated into a protein.
Capping involves the addition of a modified guanine nucleotide to the 5' end of the pre-mRNA, which helps protect the mRNA from degradation and assists in its export from the nucleus. Splicing then removes the introns from the pre-mRNA and joins the exons together, creating a continuous coding sequence. Finally, polyadenylation adds a string of adenine nucleotides to the 3' end of the pre-mRNA, contributing to mRNA stability and facilitating its interaction with ribosomes during translation.
Overall, pre-mRNA represents the initial transcript synthesized during gene transcription in eukaryotes, containing both coding and non-coding regions. It undergoes several modifications, including capping, splicing, and polyadenylation, to produce mature mRNA capable of being translated into functional proteins.
Common Misspellings for PRE MRNA
Etymology of PRE MRNA
The term "pre-mRNA" is a combination of two words: "pre-" and "mRNA".
1. "Pre-": The prefix "pre-" comes from the Latin word "prae" meaning "before" or "in front of". It is used to indicate something that occurs or exists before a particular event or state. In the case of pre-mRNA, it indicates that the molecule is the precursor or precursor form of messenger RNA.
2. "mRNA": The abbreviation "mRNA" stands for "messenger RNA". It is a type of RNA molecule that carries the genetic information from DNA to the ribosomes, where it is used as a template for protein synthesis.
Combining these two components, "pre-mRNA" refers to the RNA molecule that is produced during transcription before it undergoes further processing, including splicing and modification, to become mature and functional mRNA.
Similar spelling words for PRE MRNA
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