POLYPROLINE Meaning and
Definition
-
Polyproline refers to a class of peptides consisting of a chain of proline amino acids. Proline is an amino acid that differs from others due to its structural characteristics and is often considered as an imino acid. Polyproline is composed of two or more proline residues linked by peptide bonds, giving rise to a linear chain structure. The term "polyproline" is derived from the Greek roots "poly" meaning many or multiple, and "proline", denoting the specific amino acid sequence.
Polyproline peptides are commonly found in nature and play crucial roles in various biological processes, especially in protein-protein interactions. They possess distinctive structural properties that confer unique functions. One of the notable characteristics is the restricted rotation around the peptide bonds due to the cyclic structure of proline, leading to a conformational rigidity. This rigidity allows polyproline helices to adopt specific shapes, enabling them to bind to specific protein targets.
Polyproline regions are frequently found in proteins involved in signal transduction, cytoskeletal organization, and protein localization. They are known to interact with modular protein domains, such as Src homology 3 (SH3) domains, WW domains, and EVH1 domains, through specific recognition interfaces. These interactions are vital for cellular processes, including cell signaling, cytoskeleton dynamics, and intracellular protein trafficking.
In summary, polyproline refers to a class of peptides composed of multiple proline amino acids connected by peptide bonds. These peptides exhibit unique structural properties and are involved in important protein-protein interactions within cells.
Common Misspellings for POLYPROLINE
- oolyproline
- lolyproline
- -olyproline
- 0olyproline
- pilyproline
- pklyproline
- pllyproline
- pplyproline
- p0lyproline
- p9lyproline
- pokyproline
- popyproline
- pooyproline
- poltproline
- polgproline
- polhproline
- poluproline
- pol7proline
- pol6proline
- polyoroline
Etymology of POLYPROLINE
The word "polyproline" is derived from the combination of two terms: "poly" and "proline".
The term "poly" derives from the Greek word "polys" meaning "many" or "multiple". It is commonly used as a prefix in English to indicate the presence of multiple or many units of something.
"Proline" refers to an amino acid commonly found in proteins. The term "proline" derives from the combining form "pro-" meaning "before" or "preceding" and the root word "in" meaning "amino".
Therefore, "polyproline" refers to a polymer or chain composed of multiple units of the amino acid proline.
Infographic
Add the infographic to your website:
