How Do You Spell POLYPLASDONE XL?

Pronunciation: [pˌɒlɪplˈasdə͡ʊn ˌɛksˈɛl] (IPA)

Polyplasdone XL is a trademarked name for a polymer used in pharmaceuticals as a disintegrant, binder, and coating agent. The spelling of this word can be explained using the International Phonetic Alphabet (IPA) as /pɒliplæzdoʊn ɛksɛl/. The "poly-" prefix refers to the many repeating units of the polymer chain, while "plasdone" likely comes from "plastic" and "-done" implies a finished or completed product. The "XL" suffix may simply denote extra-large or extended-release properties.

POLYPLASDONE XL Meaning and Definition

  1. Polyplasdone XL is a trademarked pharmaceutical ingredient used primarily as a binder in tablet formulations. It is a type of insoluble polyvinylpyrrolidone (PVP) polymer utilized to enhance the cohesiveness and compactness of powdered drug formulations during compression into tablets. Polyplasdone XL is engineered to possess a high molecular weight, which imparts its excellent binding properties.

    To elaborate, Polyplasdone XL is a fine, free-flowing, white to off-white powder that is highly dispersible in water and organic solvents. It acts as a binder by forming a film around the active drug particles when mixed with other tablet excipients. This film aids in the uniform distribution of the drug and prevents it from separating or being released too quickly upon ingestion.

    Furthermore, Polyplasdone XL offers several additional benefits to pharmaceutical formulations. For instance, it aids in the disintegration and dissolution of tablets, improving their bioavailability and ensuring consistent drug release. It also exhibits minimal hygroscopicity and good compatibility with a wide range of active pharmaceutical ingredients and excipients.

    Overall, the inclusion of Polyplasdone XL in tablet formulations helps ensure the mechanical strength and integrity of the tablets, thereby enhancing their stability, handling, and ease of administration. Its utilization in pharmaceutical products has proven to be a reliable and effective method for producing high-quality tablets.

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