The word "Polygeline" is spelled with a combination of Greek and Latin roots. The prefix "poly-" means "many", while "geline" is a short form of the Latin word "gelatin", meaning a jelly-like substance. The correct way to pronounce this word is /pɒliːdʒɛliːn/, with the stress on the third syllable. The phonetic transcription shows that the first syllable is pronounced with an "o" sound similar to "olive", while the second syllable has a long "e" sound like "bee". Together, the pronunciation of this word is clear and easy to comprehend.
Polygeline is a compound term that stems from the combination of two words: "poly" and "geline." It refers to a synthetic watery colloidal substance that is commonly used as a plasma volume expander.
Polygeline, also known by its trade names like "Haemaccel" or "Gelac," is administered intravenously to increase blood volume and enhance circulation in cases of blood loss or hypovolemia. It is a hypertonic solution composed of polyvinylpyrrolidone (PVP) and polyethylene glycol (PEG), both of which contribute to its colloidal nature.
As a plasma volume expander, polygeline works by attracting water from the surrounding tissues into the bloodstream, thereby increasing the blood volume. This expansion helps maintain an adequate blood pressure, ensuring sufficient oxygen and nutrients are delivered to the body's tissues. It can be used in emergency situations, during surgeries, or in critical care settings where prompt volume resuscitation is required.
Polygeline has a relatively short duration of action and is metabolized and excreted by the kidneys. It is generally well tolerated, although, like any medication, it may have potential side effects or contraindications, such as hypersensitivity reactions or kidney dysfunction. Therefore, it should be used with caution and according to the healthcare professional's guidance.