PLECTIN GENE Meaning and
Definition
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The plectin gene is a specific gene that encodes plectin, a structural and regulatory protein found in various tissues and cells throughout the body. Plectin is classified as a cytolinker protein, meaning that it plays a crucial role in linking different cellular components together within the cytoskeleton. The plectin gene is responsible for providing instructions for the synthesis of plectin, ensuring its production within cells.
Plectin is vital for maintaining cellular integrity and stability, as it forms bridges between intermediate filaments and other cytoskeletal components. By connecting these structures, plectin contributes to the overall strength and resilience of cells, allowing them to withstand mechanical stress and maintain their structural integrity. Moreover, plectin participates in cellular movement, cell division, and intracellular transport by anchoring and organizing specific components of the cytoskeleton.
Mutations in the plectin gene have been associated with several inherited disorders, collectively known as plectinopathies. These conditions can affect various tissues and organs, resulting in a range of symptoms such as skin blistering, muscle weakness, and neurological abnormalities. Understanding the plectin gene and its role in cellular function is essential for comprehending the molecular mechanisms underlying these disorders and potentially developing targeted therapies.
In summary, the plectin gene is responsible for encoding plectin, a crucial protein involved in maintaining cellular structure and function. Mutations in this gene can lead to various inherited disorders with diverse clinical manifestations.
Common Misspellings for PLECTIN GENE
- olectin gene
- llectin gene
- 0lectin gene
- pkectin gene
- ppectin gene
- poectin gene
- plwctin gene
- plsctin gene
- pldctin gene
- plrctin gene
- pl4ctin gene
- pl3ctin gene
- plextin gene
- plevtin gene
- pleftin gene
- pledtin gene
- plecrin gene
- plecfin gene
- plecgin gene
- plecyin gene
Etymology of PLECTIN GENE
The word "plectin" is derived from the Greek word "plektein", meaning "to weave". It is related to the word "plektron", which means "weaver's shuttle" or "instrument for weaving". The term "plectin" was adopted to describe a type of filament-binding protein that plays a role in the formation and maintenance of the cytoskeleton in cells. The addition of "gene" to form "plectin gene" signifies the specific genetic sequence responsible for encoding the plectin protein.
