How Do You Spell PLATELET MEMBRANE GLYCOPROTEIN IX?

Pronunciation: [plˈe͡ɪtlət mˈɛmbɹe͡ɪn ɡlˈa͡ɪkəpɹˌə͡ʊtiːn ɹˌə͡ʊmən nˈa͡ɪn] (IPA)

Platelet Membrane Glycoprotein IX is a complex term in the medical field. It is pronounced as /ˈpleɪtlɪt ˈmɛmbran ɡlaɪkəʊˌproʊtiːn 'aɪks/. The IPA phonetic transcription breaks down the word in a phonetic format to give the correct pronunciation. The word "platelet" refers to a blood cell responsible for clotting, while "membrane" describes a thin layer that encloses the cell. "Glycoprotein IX" refers to a protein component found on the platelet surface that plays an essential role in blood clotting.

PLATELET MEMBRANE GLYCOPROTEIN IX Meaning and Definition

1. Platelet Membrane Glycoprotein IX (also known as Glycoprotein IX or CD42a), is a protein that is primarily expressed on the surface of platelets, which are small blood cells involved in clot formation and wound healing. Platelets play a vital role in the formation of blood clots to prevent excessive bleeding.

   The Platelet Membrane Glycoprotein IX is a member of the Leukocyte Common Antigen (LCA) family and is characterized by its unique structure and functions. It is a heavily glycosylated type I transmembrane protein that consists of an extracellular domain, a transmembrane domain, and a cytoplasmic tail. This protein acts as a receptor for von Willebrand factor, which is crucial for platelet adhesion to the damaged blood vessel walls.

   The interaction of the Platelet Membrane Glycoprotein IX with von Willebrand factor is essential for forming stable platelet aggregates, which ultimately lead to blood clot formation. Additionally, this protein is involved in the activation of platelets and their aggregation in response to various stimuli, including thrombin and collagen.

   Defects or mutations in the gene encoding Platelet Membrane Glycoprotein IX have been associated with Bernard-Soulier syndrome, an inherited bleeding disorder characterized by abnormal platelet function. Understanding the structure, function, and interactions of this protein provides valuable insights into platelet function and the mechanisms underlying clot formation.

Common Misspellings for PLATELET MEMBRANE GLYCOPROTEIN IX

• platelet membrane glycopreotein iv
• olatelet membrane glycoprotein ix
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