How Do You Spell PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR?

Pronunciation: [plˈe͡ɪtlət dɪɹˈa͡ɪvd ɡɹˈə͡ʊθ fˈaktəɹ ˈalfə ɹɪsˈɛptə] (IPA)

The spelling of Platelet Derived Growth Factor alpha Receptor is quite complex due to its technical nature. In IPA phonetic transcription, it can be represented as /ˈpleɪtlət dɪˈraɪvd ɡrəʊθ ˈfæktər ˈælfə ri:septər/. The word's spelling includes a combination of silent letters and the use of Greek letters for symbols, indicating its scientific origin. The Platelet Derived Growth Factor alpha Receptor is an essential protein involved in cell growth and regeneration, making it a critical component of biology research.

PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR Meaning and Definition

1. Platelet-derived growth factor alpha receptor (PDGFRA) is a transmembrane receptor protein that plays a critical role in cell signaling and regulation of cell proliferation and differentiation. It belongs to the receptor tyrosine kinase (RTK) family and is expressed on the cell surface of various cell types, including smooth muscle cells, fibroblasts, and certain types of stem cells.

   PDGFRA is activated by binding to its specific ligand, platelet-derived growth factor (PDGF), which is released by platelets and other cells in response to tissue injury or inflammation. Upon ligand binding, PDGFRA undergoes dimerization and autophosphorylation, leading to the activation of its intracellular kinase domain. This initiates a signaling cascade that triggers various cellular responses, including cell growth, migration, and survival.

   Abnormal activation or mutation of PDGFRA has been implicated in the development and progression of various diseases, including cancers and fibrotic disorders. In cancer, overexpression or activating mutations of PDGFRA can lead to uncontrolled cell proliferation and tumor growth. Therefore, PDGFRA has emerged as a potential therapeutic target for the treatment of certain types of cancer.

   In summary, the platelet-derived growth factor alpha receptor is a cell surface receptor protein that plays a crucial role in cell signaling and regulation of cell growth and differentiation. Its signaling pathway is involved in various physiological and pathological processes, making it an important target for therapeutic intervention.

Common Misspellings for PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR

• olatelet derived growth factor alpha receptor
• llatelet derived growth factor alpha receptor
• -latelet derived growth factor alpha receptor
• 0latelet derived growth factor alpha receptor
• pkatelet derived growth factor alpha receptor
• ppatelet derived growth factor alpha receptor
• poatelet derived growth factor alpha receptor
• plztelet derived growth factor alpha receptor
• plstelet derived growth factor alpha receptor
• plwtelet derived growth factor alpha receptor
• plqtelet derived growth factor alpha receptor
• plarelet derived growth factor alpha receptor
• plafelet derived growth factor alpha receptor
• plagelet derived growth factor alpha receptor
• playelet derived growth factor alpha receptor
• pla6elet derived growth factor alpha receptor
• pla5elet derived growth factor alpha receptor
• platwlet derived growth factor alpha receptor
• platslet derived growth factor alpha receptor
• platdlet derived growth factor alpha receptor